Drug points: Quinolones may induce hepatitis
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چکیده
منابع مشابه
Fluorinated 4-quinolones induce hyperproduction of interleukin 2.
The fluorinated 4-quinolones are a "new" group of antibiotics with a broad antibacterial spectrum. They are already widely used in clinical practice. Previous studies have shown that these drugs increase the uptake of [3H]thymidine into DNA of mitogen-stimulated lymphocytes but inhibit cell growth and immunoglobulin secretion. This study shows that the 4-quinolones strongly (up to 100 times) in...
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Fixed drug eruptions (FDE) are the common dermatological adverse drug reaction accounts for 16-21% of all cutaneous drug reactions in India. Drugs most frequently implicated in FDE are antimicrobials, anticonvulsants, and nonsteroidal antiinflammatory drugs. Here, we report a rare case of bullous FDE due to ciprofloxacin followed by ofloxacin administration.
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Successful desensitization protocols have been reported in patients with fi xed drug eruption (FDE) [1-3]. In chronic diseases, it would be desirable to sustain the tolerance achieved after desensitization. Maintained tolerance has been reported in immunoglobulin (Ig) E–mediated hypersensitivity reactions [4,5], but not in FDE. We report the case of a 28-year-old female with cystic fi brosis wh...
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DRESS is a rare but life threatening drug allergic disease. The value of skin tests, especially patch-tests (PT) for defining the culprit drug were recently reported. Nevertheless DRESS has been associated with high risk of disease flare linked to drug rechallenge (culprit drug or not) or viral reactivation . In this study we analyzed the frequency of patch test-induced DRESS flares. Method Bet...
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ژورنال
عنوان ژورنال: BMJ
سال: 1997
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.314.7084.869